Publications

View a complete list of Lavine lab publications

Selected Publications

• Liu J, Ma P, Lai L, et al. Transcriptional and Immune Landscape of Cardiac Sarcoidosis. Circ Res. 2022;131(8):654-669. doi:10.1161/CIRCRESAHA.121.320449
• Tseliou E, Lavine KJ, Wever-Pinzon O, et al. Biology of myocardial recovery in advanced heart failure with long-term mechanical support. J Heart Lung Transplant. 2022;41(10):1309-1323. doi:10.1016/j.healun.2022.07.007
• Kopecky BJ, Dun H, Amrute JM, et al. Donor Macrophages Modulate Rejection After Heart Transplantation. Circulation. 2022;146(8):623-638. doi:10.1161/CIRCULATIONAHA.121.057400
• Dmytrenko O, Lavine KJ. Cardiovascular Tropism and Sequelae of SARS-CoV-2 Infection. Viruses. 2022;14(6):1137. Published 2022 May 25. doi:10.3390/v14061137
• Jimenez J, Lavine KJ. The Dynamic Role of Cardiac Macrophages in Aging and Disease. Curr Cardiol Rep. 2022;24(8):925-933. doi:10.1007/s11886-022-01714-4
• Lavine KJ, Liu Y. The dynamic cardiac cellular landscape: visualization by molecular imaging. Nat Rev Cardiol. 2022;19(6):345-347. doi:10.1038/s41569-022-00702-z
• Bredemeyer AL, Amrute JM, Koenig AL, et al. Derivation of extra-embryonic and intra-embryonic macrophage lineages from human pluripotent stem cells. Development. 2022;149(8):dev200016. doi:10.1242/dev.200016
• Amrute JM, Perry AM, Anand G, et al. Cell specific peripheral immune responses predict survival in critical COVID-19 patients. Nat Commun. 2022;13(1):882. Published 2022 Feb 15. doi:10.1038/s41467-022-28505-3
• Feng G, Bajpai G, Ma P, et al. CCL17 Aggravates Myocardial Injury by Suppressing Recruitment of Regulatory T Cells. Circulation. 2022;145(10):765-782. doi:10.1161/CIRCULATIONAHA.121.055888
• Koenig AL, Lavine KJ. Leveraging FPR2 Agonists to Resolve Inflammation and Improve Outcomes Following Myocardial Infarction. JACC Basic Transl Sci. 2021;6(8):690-692. Published 2021 Aug 23. doi:10.1016/j.jacbts.2021.07.009
• Verma AK, Lavine KJ, Lin CY. Myocarditis after Covid-19 mRNA Vaccination. N Engl J Med. 2021 Sep 30;385(14):1332-1334. doi: 10.1056/NEJMc2109975. Epub 2021 Aug 18. PMID: 34407340; PMCID: PMC8385564.
• Wong NR, Mohan J, Kopecky BJ, Guo S, Du L, Leid J, Feng G, Lokshina I, Dmytrenko O, Luehmann H, Bajpai G, Ewald L, Bell L, Patel N, Bredemeyer A, Weinheimer CJ, Nigro JM, Kovacs A, Morimoto S, Bayguinov PO, Fisher MR, Stump WT, Greenberg M, Fitzpatrick JAJ, Epelman S, Kreisel D, Sah R, Liu Y, Hu H, Lavine KJ. Resident cardiac macrophages mediate adaptive myocardial remodeling. Immunity. 2021 Sep 14;54(9):2072-2088.e7. doi: 10.1016/j.immuni.2021.07.003. Epub 2021 Jul 27. PMID: 34320366; PMCID: PMC8446343.
• Koenig AL, Lavine KJ. Leveraging FPR2 Agonists to Resolve Inflammation and Improve Outcomes Following Myocardial Infarction. JACC Basic Transl Sci. 2021 Aug 23;6(8):690-692. doi: 10.1016/j.jacbts.2021.07.009. PMID: 34466755; PMCID: PMC8385647.
• Gropler MRF, Lipshultz SE, Wilkinson JD, Towbin JA, Colan SD, Canter CE, Lavine KJ, Simpson KE. Pediatric and adult dilated cardiomyopathy are distinguished by distinct biomarker profiles. Pediatr Res. 2021 Aug 17. doi: 10.1038/s41390-021-01698-x. Epub ahead of print. PMID: 34404929.
• Hahn, L.R. Gokanapudy et al. TET2 Driven Clonal Hematopoiesis Promotes Allograft Tolerance in a Mouse Heart Transplant Model. The Journal of Heart and Lung Transplantation, Volume 40, Issue 4, S228.

• Bailey AL, Dmytrenko O, Greenberg L, Bredemeyer AL, Ma P, Liu J, Penna V, Winkler ES, Sviben S, Brooks E, Nair AP, Heck KA, Rali AS, Simpson L, Saririan M, Hobohm D, Stump WT, Fitzpatrick JA, Xie X, Zhang X, Shi PY, Hinson JT, Gi WT, Schmidt C, Leuschner F, Lin CY, Diamond MS, Greenberg MJ, Lavine KJ. SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis. JACC Basic Transl Sci. 2021 Feb 26. doi: 10.1016/j.jacbts.2021.01.002. PMID: 33681537.
• Benjamin J. Kopecky, Christian Frye, Yuriko Terada, Keki R. Balsara, Daniel Kreisel, and Kory J. Lavine Role of Donor Macrophages After Heart and Lung Transplantation. AM J Transplant.  2019 Dec 18. doi: 10.1111/ajt.15751.
• Li W, Feng G, Gauthier JM, Lokshina I, Higashikubo R, Evans S, Liu X, Hassan A, Tanaka S, Cicka M, Hsiao HM, Ruiz-Perez D, Bredemeyer A, Gross RW, Mann DL, Tyurina YY, Gelman AE, Kagan VE, Linkermann A, Lavine KJ, Kreisel D. Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation. J Clin Invest. 2019 Feb 26;129(6):2293-2304.
• Heo GS, Kopecky B, Sultan D, Ou M, Feng G, Bajpai G, Zhang X, Luehmann H, Detering L, Su Y, Leuschner F, Combadière C, Kreisel D, Gropler RJ, Brody SL, Liu Y, Lavine KJ. Molecular Imaging Visualizes Recruitment of Inflammatory Monocytes and Macrophages to the Injured Heart. Circ Res. 2019 Mar 15;124(6):881-890.
• Bajpai G, Bredemeyer A, Li W, Zaitsev K, Koenig AL, Lokshina I, Mohan J, Ivey B, Hsiao HM, Weinheimer C, Kovacs A, Epelman S, Artyomov M, Kreisel D, Lavine KJ. Tissue Resident CCR2- and CCR2+ Cardiac Macrophages Differentially Orchestrate Monocyte Recruitment and Fate Specification Following Myocardial Injury. Circ Res. 2019 Jan 18;124(2):263-278.
• Lavine KJ, Pinto AR, Epelman S, Kopecky BJ, Clemente-Casares X, Godwin J, Rosenthal N, Kovacic JC. The Macrophage in Cardiac Homeostasis and Disease: JACC Macrophage in CVD Series (Part 4). J Am Coll Cardiol. 2018 Oct 30;72(18):2213-2230.
• Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ. The human heart contains distinct macrophage subsets with divergent origins and functions. Nat Med. 2018 Aug;24(8):1234-1245.
• Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ. Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. Circ Res. 2016 May 13;118(10):1498-511.